Nature Communications (Aug 2018)

Enantioselective radical conjugate additions driven by a photoactive intramolecular iminium-ion-based EDA complex

  • Zhong-Yan Cao,
  • Tamal Ghosh,
  • Paolo Melchiorre

DOI
https://doi.org/10.1038/s41467-018-05375-2
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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In enantioselective catalysis, electron donor–acceptor (EDA) complexes are usually photochemically activated in an intermolecular fashion. Here, the authors report the stereoselective conjugate addition to β-substituted cyclic enones proceeding without external photoredox catalysts via an intramolecular EDA complex.