Measuring the size and decay dynamics of the HIV-1 latent reservoir

Runxia Liu; Allison A. Catalano; Ya-Chi Ho

Cell Reports Medicine (Apr 2021)

Measuring the size and decay dynamics of the HIV-1 latent reservoir

Runxia Liu,
Allison A. Catalano,
Ya-Chi Ho

Affiliations

Runxia Liu: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06519, USA
Allison A. Catalano: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Epidemiology of Microbial Diseases, Yale University School of Public Health, New Haven, CT 06519, USA
Ya-Chi Ho: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06519, USA; Corresponding author

Journal volume & issue: Vol. 2, no. 4
p. 100249

Abstract

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Measuring HIV-1 latent reservoir is essential for HIV-1 cure strategies. Levy et al.1 developed a multiplex droplet digital PCR (ddPCR) assay—5-target intact proviral DNA assay—to detect multiple regions of HIV-1 proviral genome and increase accuracy.

Published in Cell Reports Medicine

ISSN: 2666-3791 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General)
Website: https://www.cell.com/cell-reports-medicine

About the journal