Journal of Applied Biomaterials & Functional Materials (Mar 2021)

Synthesis and properties of Sr doping α-tricalcium phosphate at low temperature

  • Zhen Yuan,
  • Jianqiang Bi,
  • Weili Wang,
  • Xiaoning Sun,
  • Lu Wang,
  • Junjie Mao,
  • Fushuai Yang

DOI
https://doi.org/10.1177/2280800021996999
Journal volume & issue
Vol. 19

Abstract

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Strontium has been widely used in bone repair materials due to its roles in promoting osteoclast apoptosis and enhancing osteoblast proliferation. In this work, synthesis and the effects of Sr 2+ doping α-tricalcium phosphate at low-temperature was studied. The setting time and the mechanical properties of α-tricalcium phosphate were controlled by varying the content of Sr 2+ . The synthesized compounds were evaluated by XRD, SEM, XPS, setting time, compressive strength, SBF immersion, and colorimetric CCK-8 assay. The results showed that Sr 2+ can improve the compressive strength and cell activity of calcium phosphate bone cement.