Problems with analyses and interpretation of data in “use of the KDQOL-36™ for assessment of health-related quality of life among dialysis patients in the United States”

Abstract

Abstract A recent article in the journal reported analyses of KDQOL-36™ survey data collected from 240,343 adults (330,412 surveys) dialyzed at a large dialysis organization in the United States during 2014–2016. The authors concluded that the KDQOL-36™ Symptoms and Problems of Kidney Disease scale had the highest mean score of the KDQOL-36™ scales. We note that this inference was erroneous because the scales are not scored on the same numeric scale. In addition, the authors found that responses to a general health perceptions item (“In general, would you say your health is excellent, very good, good, fair, or poor”) was not significantly associated with any of the 5 KDQOL-36 scale scores. In contrast, we find significant and noteworthy correlations in two other datasets. These analytic issues call into question the accuracy and validity of the conclusions of this paper.

Keywords

• Renal disease
• Health-related quality of life, KDQOL-36™