Педиатрическая фармакология (May 2022)
Modern Approaches to the Management of Children with Atypical Hemolytic Uremic Syndrome
- Khadizha M. Emirova,
- Tatiana Yu. Abaseeva,
- Alexander A. Baranov,
- Nato D. Vashakmadze,
- Elena A. Vishneva,
- Galina A. Generalova,
- Ekaterina Yu. Zakharova,
- Tatiana A. Kaluzhnaya,
- Sergey I. Kutsev,
- Leyla S. Namazova-Baranova,
- Tamara P. Makarova,
- Tea V. Margieva,
- Sofya A. Mstislavskaya,
- Aleksandr L. Muzurov,
- Tatiana E. Pankratenko,
- Marina M. Shilova,
- Marina V. Fedoseenko
Affiliations
- Khadizha M. Emirova
- A.I. Yevdokimov Moscow State University of Medicine and Dentistry; Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital
- Tatiana Yu. Abaseeva
- A.I. Yevdokimov Moscow State University of Medicine and Dentistry; Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital
- Alexander A. Baranov
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Sechenov First Moscow State Medical University
- Nato D. Vashakmadze
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
- Elena A. Vishneva
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
- Galina A. Generalova
- Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital; Russian Medical Academy of Continuing Professional Education
- Ekaterina Yu. Zakharova
- Research Centre for Medical Genetics
- Tatiana A. Kaluzhnaya
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
- Sergey I. Kutsev
- Research Centre for Medical Genetics
- Leyla S. Namazova-Baranova
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University; Belgorod National Research University
- Tamara P. Makarova
- Kazan State Medical University
- Tea V. Margieva
- Sechenov First Moscow State Medical University
- Sofya A. Mstislavskaya
- A.I. Yevdokimov Moscow State University of Medicine and Dentistry; Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital
- Aleksandr L. Muzurov
- Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital; Russian Medical Academy of Continuing Professional Education
- Tatiana E. Pankratenko
- Center of Gravitational Blood Surgery and Hemodialysis of Saint Vladimir Children’s Clinical Hospital
- Marina M. Shilova
- Pirogov Russian National Research Medical University
- Marina V. Fedoseenko
- Research Institute of Pediatrics and Children's Health in Petrovsky National Research Centre of Surgery; Pirogov Russian National Research Medical University
- DOI
- https://doi.org/10.15690/pf.v19i2.2400
- Journal volume & issue
-
Vol. 19,
no. 2
pp. 127 – 152
Abstract
Experts of the Union of Pediatricians of Russia have developed modern guidelines on management of children with atypical hemolytic uremic syndrome (aHUS). aHUS is ultra-rare (orphan) disease with progressive and relapsing course during the life with potentially life-threatening state. This article covers issues of disease etiology, pathogenesis, and classification. Specific attention is paid to the diagnosis, differential diagnosis, and therapy of aHUS according to the evidence-based approaches.
Keywords
