The value of vitamin D for the health of perimenopausal women

Abstract

In recent years, there have been reports of the effect of vitamin D on the intensity of early manifestations of menopausal syndrome (hot flushes, mood instability and symptoms of depression, sleep disorders) in perimenopausal women. This review of Russian and foreign literature presents the latest data on the role of vitamin D in maintaining the physical and emotional health of women during this period of life. According to the results of the study, it was found that vitamin D significantly reduces the intensity of early manifestations of climacteric syndrome in perimenopausal women. Prevention of vitamin D deficiency has a positive effect on the health of women in perimenopause, reducing the severity of manifestations of menopausal syndrome.On the basis of the studied literature data it is shown that the effect of calciferol on serotonin metabolism is similar to the effect of serotonin reuptake inhibitors, which are used in therapy of fever episodes.Inclusion of vitamin D (if there is a deficiency of it) in the complex therapy helps to cope with depression and insomnia. A normal supply of vitamin D provides maintenance of an optimal concentration of intracellular calcium in nerve cells, which reduces the likelihood of depression. During the perimenopause, in addition to the normalization of physical health, it is necessary to maintain its mental component. It has been proven that taking vitamin D in addition to menopausal hormonal therapy can quickly improve the emotional background, sexual function and quality of life. But still, there are cases when taking vitamin D does not cause positive changes. Most often, this is due to polymorphism of vitamin D receptors. The problem needs further study, as there is no clearly formulated treatment tactics in such situations.

Keywords

• perimenopause
• menopausal syndrome
• hot flashes
• depression
• sleep disorders
• vitamin d