PLoS ONE (Jan 2021)

Improved privacy preserving method for periodical SRS publishing.

  • Wei Huang,
  • Tong Yi,
  • Haibin Zhu,
  • Wenqian Shang,
  • Weiguo Lin

DOI
https://doi.org/10.1371/journal.pone.0250457
Journal volume & issue
Vol. 16, no. 4
p. e0250457

Abstract

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Spontaneous reporting systems (SRSs) are used to collect adverse drug events (ADEs) for their evaluation and analysis. Periodical SRS data publication gives rise to a problem where sensitive, private data can be discovered through various attacks. The existing SRS data publishing methods are vulnerable to Medicine Discontinuation Attack(MD-attack) and Substantial symptoms-attack(SS-attack). To remedy this problem, an improved periodical SRS data publishing-PPMS(k, θ, ɑ)-bounding is proposed. This new method can recognize MD-attack by ensuring that each equivalence group contains at least k new medicine discontinuation records. The SS-attack can be thwarted using a heuristic algorithm. Theoretical analysis indicates that PPMS(k, θ, ɑ)-bounding can thwart the above-mentioned attacks. The experimental results also demonstrate that PPMS(k, θ, ɑ)-bounding can provide much better protection for privacy than the existing method and the new method dose not increase the information loss. PPMS(k, θ, ɑ)-bounding can improve the privacy, guaranteeing the information usability of the released tables.