GltS regulates biofilm formation in methicillin-resistant Staphylococcus aureus

Miho Shibamura-Fujiogi; Xiaogang Wang; Wiriya Maisat; Sophia Koutsogiannaki; Yunan Li; Yue Chen; Jean C. Lee; Koichi Yuki

doi:10.1038/s42003-022-04239-2

Communications Biology (Nov 2022)

GltS regulates biofilm formation in methicillin-resistant Staphylococcus aureus

Miho Shibamura-Fujiogi,
Xiaogang Wang,
Wiriya Maisat,
Sophia Koutsogiannaki,
Yunan Li,
Yue Chen,
Jean C. Lee,
Koichi Yuki

Affiliations

Miho Shibamura-Fujiogi: Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children’s Hospital
Xiaogang Wang: Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
Wiriya Maisat: Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children’s Hospital
Sophia Koutsogiannaki: Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children’s Hospital
Yunan Li: Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota
Yue Chen: Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota
Jean C. Lee: Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School
Koichi Yuki: Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children’s Hospital

DOI: https://doi.org/10.1038/s42003-022-04239-2
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 17

Abstract

Read online

Impaired intake of exogenous glutamate, due to deficiency of the GltS sodium-glutamate transporter, promotes increased Staphylococcus aureus biofilm formation in vitro and in vivo.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal