A case of sclerosing angiomatoid nodular transformation with central calcification

Eri Nakamura, MD; Yasutaka Ichikawa, MD, PhD; Kensuke Domae, MD; Yuzuna Aoki, MD; Yoichi Kozaki, MD; Miki Usui, MD; Akito Taniguchi, MD; Motonori Nagata, MD, PhD; Hajime Sakuma, MD, PhD

Radiology Case Reports (Mar 2025)

A case of sclerosing angiomatoid nodular transformation with central calcification

Eri Nakamura, MD,
Yasutaka Ichikawa, MD, PhD,
Kensuke Domae, MD,
Yuzuna Aoki, MD,
Yoichi Kozaki, MD,
Miki Usui, MD,
Akito Taniguchi, MD,
Motonori Nagata, MD, PhD,
Hajime Sakuma, MD, PhD

Affiliations

Eri Nakamura, MD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Yasutaka Ichikawa, MD, PhD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan; Corresponding author.
Kensuke Domae, MD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Yuzuna Aoki, MD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Yoichi Kozaki, MD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Miki Usui, MD: Department of Pathology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Akito Taniguchi, MD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Motonori Nagata, MD, PhD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan
Hajime Sakuma, MD, PhD: Department of Radiology, Mie University, 2-174 Edobashi, Tsu, 514-8507 Mie, Japan

Journal volume & issue: Vol. 20, no. 3
pp. 1380 – 1385

Abstract

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Sclerosing angiomatoid nodular transformation (SANT) is a rare benign vascular disease and mostly discovered incidentally in asymptomatic patients. Since SANT grows over time and it is often difficult to rule out malignancy on imaging, splenectomy is frequently the treatment of choice. Image findings of SANT have been reported as low signal intensity on T2-weighted magnetic resonance (MR) images and a characteristic enhancement pattern on dynamic contrast-enhanced computed tomography (CT) and MR images. This report describes a case of a 43-year-old woman with SANT presenting multiple calcifications on CT images, and discusses the characteristics and mechanism of the calcification, while reviewing previously reported cases of SANT.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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