Nature Communications (Jun 2022)

Ultrasensitive detection of local acoustic vibrations at room temperature by plasmon-enhanced single-molecule fluorescence

  • Mingcai Xie,
  • Hanyu Liu,
  • Sushu Wan,
  • Xuxing Lu,
  • Daocheng Hong,
  • Yu Du,
  • Weiqing Yang,
  • Zhihong Wei,
  • Susu Fang,
  • Chen-Lei Tao,
  • Dan Xu,
  • Boyang Wang,
  • Siyu Lu,
  • Xue-Jun Wu,
  • Weigao Xu,
  • Michel Orrit,
  • Yuxi Tian

DOI
https://doi.org/10.1038/s41467-022-30955-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

Read online

.Sensitive detection of weak acoustic signals at nanometer scale is challenging. Here, the authors present an acoustic detection system based on a single molecule as a probe, where frequency and amplitude of acoustic vibrations can be extracted from its minute variations in distance to the surface of a plasmonic gold nanorod.