Lnc-PICSAR contributes to cisplatin resistance by miR-485-5p/REV3L axis in cutaneous squamous cell carcinoma

Wang Dan; Zhou Xiaoqiang; Yin Jing; Zhou Yang

doi:10.1515/biol-2020-0049

Open Life Sciences (Jul 2020)

Lnc-PICSAR contributes to cisplatin resistance by miR-485-5p/REV3L axis in cutaneous squamous cell carcinoma

Wang Dan,
Zhou Xiaoqiang,
Yin Jing,
Zhou Yang

Affiliations

Wang Dan: Plastic Surgery Center, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214000, China
Zhou Xiaoqiang: Department of Dermatology, Medical College of Shaoguan University, Shaoguan, 512026, China
Yin Jing: Department of Interventional Vascular, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214000, China
Zhou Yang: Department of Dermatology, Yancheng First People’s Hospital, Jiangsu Province, No.166 yulong west road, Yancheng, Jiangsu, 224001, China

DOI: https://doi.org/10.1515/biol-2020-0049
Journal volume & issue: Vol. 15, no. 1
pp. 488 – 500

Abstract

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Dysregulation of long noncoding RNAs (lncRNAs) is associated with drug resistance in multiple cancers. We explored the roles of lncRNA p38 inhibited cutaneous squamous cell carcinoma-associated lincRNA (PICSAR) in cisplatin (DDP) resistance of cutaneous squamous cell carcinoma (CSCC).

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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