Cancers (Oct 2023)

Artificial Intelligence and Lung Cancer: Impact on Improving Patient Outcomes

  • Zainab Gandhi,
  • Priyatham Gurram,
  • Birendra Amgai,
  • Sai Prasanna Lekkala,
  • Alifya Lokhandwala,
  • Suvidha Manne,
  • Adil Mohammed,
  • Hiren Koshiya,
  • Nakeya Dewaswala,
  • Rupak Desai,
  • Huzaifa Bhopalwala,
  • Shyam Ganti,
  • Salim Surani

DOI
https://doi.org/10.3390/cancers15215236
Journal volume & issue
Vol. 15, no. 21
p. 5236

Abstract

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Lung cancer remains one of the leading causes of cancer-related deaths worldwide, emphasizing the need for improved diagnostic and treatment approaches. In recent years, the emergence of artificial intelligence (AI) has sparked considerable interest in its potential role in lung cancer. This review aims to provide an overview of the current state of AI applications in lung cancer screening, diagnosis, and treatment. AI algorithms like machine learning, deep learning, and radiomics have shown remarkable capabilities in the detection and characterization of lung nodules, thereby aiding in accurate lung cancer screening and diagnosis. These systems can analyze various imaging modalities, such as low-dose CT scans, PET-CT imaging, and even chest radiographs, accurately identifying suspicious nodules and facilitating timely intervention. AI models have exhibited promise in utilizing biomarkers and tumor markers as supplementary screening tools, effectively enhancing the specificity and accuracy of early detection. These models can accurately distinguish between benign and malignant lung nodules, assisting radiologists in making more accurate and informed diagnostic decisions. Additionally, AI algorithms hold the potential to integrate multiple imaging modalities and clinical data, providing a more comprehensive diagnostic assessment. By utilizing high-quality data, including patient demographics, clinical history, and genetic profiles, AI models can predict treatment responses and guide the selection of optimal therapies. Notably, these models have shown considerable success in predicting the likelihood of response and recurrence following targeted therapies and optimizing radiation therapy for lung cancer patients. Implementing these AI tools in clinical practice can aid in the early diagnosis and timely management of lung cancer and potentially improve outcomes, including the mortality and morbidity of the patients.

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