mSphere (Aug 2021)
Diagnostic Accuracy of Dried Blood Spots Collected on HemaSpot HF Devices Compared to Venous Blood Specimens To Estimate Measles and Rubella Seroprevalence
- Christine Prosperi,
- Ojas Kaduskar,
- Vaishali Bhatt,
- Alvira Z. Hasan,
- Jeromie W. Vivian Thangaraj,
- Muthusamy S. Kumar,
- R. Sabarinathan,
- Saravana Kumar,
- Augustine Duraiswamy,
- Gururaj Rao Deshpande,
- Ullas Padinjaremattathil Thankappan,
- Sanjay L. Chauhan,
- Ragini N. Kulkarni,
- Avi Kumar Bansal,
- Itta K. Chaaithanya,
- Neha R. Salvi,
- Sandeep Sharma,
- William J. Moss,
- Lucky Sangal,
- Nivedita Gupta,
- Manoj V. Murherkar,
- Sanjay M. Mehendale,
- Gajanan N. Sapkal,
- Kyla Hayford
Affiliations
- Christine Prosperi
- Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
- Ojas Kaduskar
- Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
- Vaishali Bhatt
- Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
- Alvira Z. Hasan
- Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
- Jeromie W. Vivian Thangaraj
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- Muthusamy S. Kumar
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- R. Sabarinathan
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- Saravana Kumar
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- Augustine Duraiswamy
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- Gururaj Rao Deshpande
- Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
- Ullas Padinjaremattathil Thankappan
- Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
- Sanjay L. Chauhan
- Department of Operational Research, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health (NIRRH), Mumbai, Maharashtra, India
- Ragini N. Kulkarni
- Department of Operational Research, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health (NIRRH), Mumbai, Maharashtra, India
- Avi Kumar Bansal
- Division of Epidemiology, ICMR-National JALMA Institute for Leprosy & Other Mycobacterial Diseases, Agra, India
- Itta K. Chaaithanya
- Department of Operational Research, Indian Council of Medical Research (ICMR)-National Institute for Research in Reproductive Health (NIRRH), Mumbai, Maharashtra, India
- Neha R. Salvi
- Department of Health Research, Model Rural Health Research Unit Dahanu, Sub District Hospital Compound, Dahanu, Maharashtra, India
- Sandeep Sharma
- Division of Epidemiology, ICMR-National JALMA Institute for Leprosy & Other Mycobacterial Diseases, Agra, India
- William J. Moss
- Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
- Lucky Sangal
- World Health Organization, Southeast Asia Region Office, New Delhi, India
- Nivedita Gupta
- Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India
- Manoj V. Murherkar
- Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India
- Sanjay M. Mehendale
- Division of Epidemiology & Communicable Diseases, Indian Council of Medical Research, New Delhi, India
- Gajanan N. Sapkal
- ORCiD
- Diagnostic Virology Group, ICMR-National Institute of Virology, Pune, Maharashtra, India
- Kyla Hayford
- Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
- DOI
- https://doi.org/10.1128/mSphere.01330-20
- Journal volume & issue
-
Vol. 6,
no. 4
Abstract
Dried blood spot (DBS) collection provides an easy, practical, and acceptable alternative to venous blood collection, especially for community-based studies, provided that results from DBS are accurate. We demonstrated high sensitivity and specificity for measles- and rubella-specific immunoglobulin G (IgG) with DBS collected via HemaSpot HF devices compared to serum samples.
