Nature Communications (Sep 2022)

Percolation transition prescribes protein size-specific barrier to passive transport through the nuclear pore complex

  • David Winogradoff,
  • Han-Yi Chou,
  • Christopher Maffeo,
  • Aleksei Aksimentiev

DOI
https://doi.org/10.1038/s41467-022-32857-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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Combining realistic coarse-grained simulations with a percolation transition theory, this study elucidates the microscopic mechanism that governs the selectivity of passive, unassisted transport through the nuclear pore complex.