Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis

Zhang Yamin; Fan Xiaoying; Yang Hua

doi:10.1515/biol-2020-0100

Open Life Sciences (Dec 2020)

Long noncoding RNA FTX ameliorates hydrogen peroxide-induced cardiomyocyte injury by regulating the miR-150/KLF13 axis

Zhang Yamin,
Fan Xiaoying,
Yang Hua

Affiliations

Zhang Yamin: Department of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, China
Fan Xiaoying: Department of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, China
Yang Hua: Department of Cardiology, The First Affiliated Hospital of Airforce Military Medical University, No. 127, Changle West Road, Xi’an, Shaanxi, 710032, China

DOI: https://doi.org/10.1515/biol-2020-0100
Journal volume & issue: Vol. 15, no. 1
pp. 1000 – 1012

Abstract

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Myocardial reperfusion is an effective therapy for acute myocardial infarction (AMI). However, ischemia/reperfusion (I/R) injury following myocardial reperfusion is a significant limitation for AMI treatment. Five prime to Xist (FTX) was recognized as a biomarker of multiple diseases, including heart disease. However, the molecular mechanism of FTX in I/R injury is unclear.

Published in Open Life Sciences

ISSN: 2391-5412 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Biology (General)
Website: http://www.degruyter.com/view/j/biol

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