Amyloidosis secondary to xanthogranulomatous pyelonephritis: A rare association

Abstract

Xanthogranulomatous pyelonephritis and secondary systemic amyloidosis are re-latively common pathologies with innumerable cases being reported now and then. However the association of these entities is an extremely uncommon occurrence with only ten cases described in the literature. Clinical remission of amyloidosis develops in a majority of these patients after re-moval of the renal lesion. We present a case of this rare association in a young female who under-went nephrectomy for a non-functioning kidney. A histopathological diagnosis of xanthogranu-lomatous pyelonephritis was made. In addition there were deposits of amyloid in the glomeruli and the interstitial blood vessels.