Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells

• Lianne E. Rotin,
• Neil MacLean,
• Ahmed Aman,
• Marcela Gronda,
• Feng-Hsu Lin,
• Rose Hurren,
• XiaoMing Wang,
• Jeffrey L Wrana,
• Alessandro Datti,
• Rima Al-awar,
• Mark D. Minden,
• Aaron D. Schimmer

Affiliations

Lianne E. Rotin

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada;Institute of Medical Science, University of Toronto, ON, Canada

Neil MacLean

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

Ahmed Aman

Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada

Marcela Gronda

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

Feng-Hsu Lin

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

Rose Hurren

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

XiaoMing Wang

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada

Jeffrey L Wrana

Samuel Lunenfeld Research Institute, Toronto, ON, Canada

Alessandro Datti

Samuel Lunenfeld Research Institute, Toronto, ON, Canada;Department of Agricultural, Food, and Environmental Sciences, University of Perugia, Italy

Rima Al-awar

Drug Discovery Program, Ontario Institute for Cancer Research, Toronto, ON, Canada;Department of Pharmacology and Toxicology, University of Toronto, ON, Canada

Mark D. Minden

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada;Institute of Medical Science, University of Toronto, ON, Canada

Aaron D. Schimmer

Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada;Institute of Medical Science, University of Toronto, ON, Canada