Dataset of aqueous humor cytokine profile in HIV patients with Cytomegalovirus (CMV) retinitis
Jayant Venkatramani Iyer,
Rupesh Agrawal,
Tun Kuan Yeo,
Dinesh V. Gunasekeran,
Praveen Kumar Balne,
Bernett Lee,
Veonice Bijin Au,
John Connolly,
Stephen C.B. Teoh
Affiliations
Jayant Venkatramani Iyer
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore; Singapore National Eye Center, Singapore; Corresponding author at: Singapore National Eye Center, 11 Third Hospital Avenue, Singapore 168751, Singapore.
Rupesh Agrawal
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
Tun Kuan Yeo
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
Dinesh V. Gunasekeran
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
Praveen Kumar Balne
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
Bernett Lee
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A⁎STAR), Singapore
Veonice Bijin Au
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A⁎STAR), Singapore
John Connolly
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A⁎STAR), Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX, USA
Stephen C.B. Teoh
National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
The data shows the aqueous humor cytokine profiling results acquired in a small cohort of 17 HIV patients clinically diagnosed with Cytomegalovirus retinitis using the FlexMAP 3D (Luminex®) platform using the Milliplex Human Cytokine® kit. Aqueous humor samples were collected from these patients at different time points (pre-treatment and at 4-weekly intervals through the 12-week course of intravitreal ganciclovir treatment) and 41 cytokine levels were analyzed at each time point. CMV DNA viral load was assessed in 8 patients at different time points throughout the course of ganciclovir treatment. The data described herein is related to the research article entitled “Aqueous humor immune factors and cytomegalovirus (CMV) levels in CMV retinitis through treatment - The CRIGSS study” (Iyer et al., 2016) [1]. Cytokine levels against the different time points which indicate the response to the given treatment and against the CMV viral load were analyzed. Keywords: Cytokines, CMV retinitis, Dataset, HIV, Luminex bead assay
