Membrane dependent processes in erythrocytes of blood of patients with pulmonary tuberculosis under the influence of helium-neon laser radiation

Abstract

The effect of frequency modulated and unmodulated He-Ne laser irradiation of blood of patients with destructive pulmonary tuberculosis in the intensive phase of chemotherapy on the level of endogenous intoxication, the processes of lipid peroxidation and activity of antioxidant enzymes was investigated. Analysis of the results of study conducted after the application of intravenous laser irradiation of blood by helium-neon laser with different frequency modulations on the background of standardized chemotherapy demonstrated that the application of frequency modulation has a pronounced positive effect on the balance of prooxidant-antioxidant processes in patients with the first diagnosed pulmonary tuberculosis, compared to single chemotherapy and influence of modulated helium-neon laser irradiation of blood. The frequency-dependent stimulation of antioxidant system and the level of inhibition of lipid peroxidation in erythrocyte membranes under the influence of laser frequency modulation on a background of chemotherapy was detected. Marked intensification of compensatory processes, especially when using a helium-neon laser with frequency modulation 5 kHz and 100 kHz, was found.

Keywords

• erythrocytes
• laser radiation
• lipid peroxidation
• antioxidant protection