Clinical evaluation of the deadline of healing of the ulcer of Buruli hurts of diameter lower or equal to 10 centimeters in pobe (Benin)

Abstract

Introduction: Ulcer of Buruli is a skin disorder due to Mycobacterium ulcerans. The objective was to estimate the deadline of healing of the hurts of the ulcer of ulcer of Buruli of diameter ≤ 10 cm. Patients and Methods: It was about a retrospective, descriptive and analytical study, realized from 2010 to 2012 in Pobè (Benin). Were included the patient, having had a positive PCR in Mycobacterium ulcerans, hurts of diameter ≤ 10 cm and treated according to the recommendations of the WHO. Results: A total of 104 patients have been included. The hurt patches represented the most frequent clinical shape (57%). The average deadline of consultation was 16.6 ±19.6 weeks. The patients presenting a hurt lesion and having consulted less than 5 weeks after the beginning of the disease, had an average deadline of healing of 85.1 ± 33.7 days versus 146.1 ± 80.2 days for those having consulted 27 weeks after the beginning of the disease (p <0.05). The average deadline of healing of forms by diameter ≤ 5cm was 105.1 ± 59.5 days versus 111. ± 44.3 days for that of hurt forms of 5 cm ≤ diameter ≤ 10 cm (p = 0.04). Conclusion: Delay in the consultation lengthens the deadline of healing of the hurts. The not hurt lesions whatever are their sizes have a deadline of healing longer than that of the hurt lesions. The results of this work should arouse other studies for new therapeutic perspectives of that affection.

Keywords

• Buruli ulcer; Hurt diameter; Evaluation