Inhibitory Effect of Prickly Ash (<i>Zanthoxylum bungeanum</i>) Seed Kernel Oil on Lipid Metabolism of Grass Carp (<i>Ctenopharyngodon idellus</i>) in High-Fat Diet

Abstract

To investigate the effect of prickly ash (Zanthoxylum bungeanum) seed kernel oil (PASO) on the lipid metabolism of grass carp (Ctenopharyngodon idellus) under a high-fat diet, PASO were added into two lipid-level (4 g/kg and 8 g/kg) diets to form four isonitrogenous diets: soybean oil (SO), PASO, high-fat soybean oil (HSO), and high-fat prickly ash seed oil (HPASO). A total of 216 healthy grass carp (9.43 ± 0.82 g) were randomly divided into four groups and fed with the four diets, respectively, for 56 days. The result showed that the viscerosomatic index (VSI) and the content of the crude lipid in the hepatopancreas and muscle was significantly higher by oil levels (p p p p ppar-γ, cebp-α, and srebp-1c was significantly down-regulated in the PASO group compared with the SO group (p ppar-α and cpt-1 were significantly up-regulated in the PASO group (p < 0.05). In conclusion, dietary PASO showed the function of reducing lipid accumulation in the fish. This reduction might be attributed to the inhibition of the lipogenesis-related genes and the stimulation of the lipolysis-related genes, which were probably modulated by the high content of linolenic acid in PASO.

Keywords

• prickly ash seed kernel oil
• growth performance
• lipid metabolism
• grass carp (<i>Ctenopharyngodon idellus</i>)