Cross-species experiments reveal widespread cochlear neural damage in normal hearing

Hari M. Bharadwaj; Alexandra R. Hustedt-Mai; Hannah M. Ginsberg; Kelsey M. Dougherty; Vijaya Prakash Krishnan Muthaiah; Anna Hagedorn; Jennifer M. Simpson; Michael G. Heinz

doi:10.1038/s42003-022-03691-4

Communications Biology (Jul 2022)

Cross-species experiments reveal widespread cochlear neural damage in normal hearing

Hari M. Bharadwaj,
Alexandra R. Hustedt-Mai,
Hannah M. Ginsberg,
Kelsey M. Dougherty,
Vijaya Prakash Krishnan Muthaiah,
Anna Hagedorn,
Jennifer M. Simpson,
Michael G. Heinz

Affiliations

Hari M. Bharadwaj: Department of Speech, Language, and Hearing Sciences, Purdue University
Alexandra R. Hustedt-Mai: Department of Speech, Language, and Hearing Sciences, Purdue University
Hannah M. Ginsberg: Weldon School of Biomedical Engineering, Purdue University
Kelsey M. Dougherty: Department of Speech, Language, and Hearing Sciences, Purdue University
Vijaya Prakash Krishnan Muthaiah: Department of Rehabilitation Sciences, University at Buffalo
Anna Hagedorn: Department of Speech, Language, and Hearing Sciences, Purdue University
Jennifer M. Simpson: Department of Speech, Language, and Hearing Sciences, Purdue University
Michael G. Heinz: Department of Speech, Language, and Hearing Sciences, Purdue University

DOI: https://doi.org/10.1038/s42003-022-03691-4
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 10

Abstract

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Cross-species experiments on chinchillas and at-risk humans suggest cochlear synaptopathy from noise exposure and aging are widespread even among individuals with clinically normal hearing status.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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