计算机化甲襞视频毛细血管镜在2型糖尿病中的运用: 对102例门诊患者的横断面研究

Abstract

Abstract Background Type 2 diabetes (T2D) is a chronic disease that negatively affects vascular health. A careful assessment of chronic complications, including microcirculation, is mandatory. The computerized nailfold video‐capillaroscopy (CNVC) accurately examines the nailfold microvasculature, but its suitability in T2D is currently under investigation. Aims To describe nailfold microvasculature in T2D patients regarding the level of glucose control and chronic microvascular and macrovascular complications. Methods This is a cross‐sectional study on 102 consecutive and unselected outpatients with T2D who had undergone CNVC examination. The examination was carried out by using an electronic video‐capillaroscope with 300x magnification. Capillaroscopic appearance and capillary changes were described according to well‐established parameters. Capillaroscopic parameters were compared between patients with poor glucose control (HbA1c ≥7%) and those with better glucose control (HbA1c 20%) than those without. Conclusion Relevant nailfold microvascular alterations were observed in T2D, most of which were associated with poor glycemic control, ED, and carotid stenosis. Further investigation is needed to recognize the role of CNVC in predicting the onset and evolution of chronic complications and monitoring the effectiveness of antihyperglycemic treatments on microcirculation.

Keywords

• 计算机化甲襞视频毛细血管镜
• 2型糖尿病
• 勃起功能障碍
• 糖尿病视网膜病变
• 慢性肾病
• 心血管疾病