Архивъ внутренней медицины (Oct 2012)

КЛИНИЧЕСКОЕ ТЕЧЕНИЕ И ИСХОДЫ ХРОНИЧЕСКОЙ ДЕЛЬТА-ИНФЕКЦИИ В ЭНДЕМИЧНОМ РЕГИОНЕ

  • Л. Ю. Ильченко,
  • Т. В. Кожанова,
  • А. А. Сарыглар,
  • Я.-Н. Д. Сонам-Байыр,
  • О. Н. Сарыг-Хаа,
  • Р. М. Соян,
  • Ю. П. Зубков,
  • О. В. Исаева,
  • К. К. Кюрегян,
  • М. И. Михайлов

DOI
https://doi.org/10.20514/2226-6704-2012-0-5-51-56
Journal volume & issue
Vol. 0, no. 5
pp. 51 – 56

Abstract

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Total 214 patients with delta infection were examined. Total 48 patients were followed annually during the observation period (2009–2011). Diagnosis of chronic hepatitis delta (CHD) was established in 78,6% (162/206) cases, liver cirrhosis (LC) — in 21,4% (44/206). HDV RNA was detected in 26,2% (56/214) patients. HDV was genotype I. Progression of CL was observed among 31,3% (15/48) of followed patients, decompensation of CL — in 8,3% (4/48), hepatocellular carcinoma — in 4,2% (2/48) cases; mortality was 29,2% (14/48), with hepatic coma and bleeding from esophageal varices as the main cause of death.

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