Therapeutic Advances in Gastroenterology (Jan 2025)

Post-colectomy enteritis—a rare complication in a patient with ulcerative colitis

  • Julia Wanzl,
  • Sandra Nagl,
  • Alanna Ebigbo,
  • Lena Anthuber,
  • Florian Sommer,
  • Michael Hoffmann,
  • David Rafael Marques Pinto,
  • Dmytro Vlasenko,
  • Irene Kleinlein,
  • Elisabeth Schnoy

DOI
https://doi.org/10.1177/17562848241309864
Journal volume & issue
Vol. 18

Abstract

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Colectomy is the surgical treatment of choice in patients with severe or complicated ulcerative colitis. Post-colectomy enteritis (PCE) is a rare condition that can develop after proctocolectomy and has been described only in a few individual cases so far. We report the case of a 46-year-old patient with severe and treatment-refractory ulcerative colitis who underwent colectomy. A few days after surgery, the patient presented with acute anemia and hematemesis. Esophagogastroduodenoscopy showed massive inflammation of the duodenum and jejunum. The life-threateningly ill patient was admitted to the intensive-care unit and treated for severe PCE with ciclosporin and corticosteroids. PCE is a distinct inflammation of the small intestine shortly after colectomy. The patient recovered fully and was discharged after prolonged recovery and long-term intensive care therapy.