Study of apolipoprotein C3 S1/S2 (C3238G, rs5128) polymorphism in Caucasian population of Eastern Siberia

Abstract

The prevalence of genotypes and alleles of polymorphic marker S1 /S2 Apolipoprotein C3 in healthy adolescent Caucasians (Russians) living in Eastern Siberia was studied. Material for research was the DNA extracted from the venous blood; genotype was determined by PCR-RFLP for each sample. In the studied sample in 88.9 % of cases genotype S1/ S1 was detected, genotype S1/S2 was found in 8.6 %, S2/S2 - in 2.5 %. The share of S2 allele was 6.8 %, which is not significantly different from the previously studied Caucasoid populations.

Keywords

• s1/s2
• apolipoprotein c3
• s1/s2
• allele
• genotype