Nature Communications (Jun 2020)

Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants

  • Aobo Huang,
  • Yu Tang,
  • Xuetao Shi,
  • Min Jia,
  • Jinheng Zhu,
  • Xiaohan Yan,
  • Huiqin Chen,
  • Yangnan Gu

DOI
https://doi.org/10.1038/s41467-020-16744-1
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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Maintaining protein integrity at the inner nuclear membrane (INM) is critical for eukaryotic cellular function. Here, using proximity-labeling proteomics, Huang et al. profile the INM in Arabidopsis and identify the CDC48 complex and PUX proteins as components of an INM protein degradation pathway.