CHIMIA (Dec 2020)
Expanding the Chemistry Palette for Radiotracer Synthesis
- Jennifer Lamb,
- Faustine d'Orchymont,
- Rachael Fay,
- Florian Gribi,
- Jose Esteban Flores,
- Melanie Gut,
- Simon Klingler,
- Patricia Pires,
- Jan Bühler,
- Shamisa Behmaneshfar,
- Amaury Guillou,
- Daniel F. Earley,
- Jason P. Holland
Affiliations
- Jennifer Lamb
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Faustine d'Orchymont
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Rachael Fay
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Florian Gribi
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Jose Esteban Flores
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Melanie Gut
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Simon Klingler
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Patricia Pires
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Jan Bühler
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Shamisa Behmaneshfar
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Amaury Guillou
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Daniel F. Earley
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- Jason P. Holland
- Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland
- DOI
- https://doi.org/10.2533/chimia.2020.946
- Journal volume & issue
-
Vol. 74,
no. 12
pp. 946 – 952
Abstract
The synthesis, characterisation and application of radiolabelled compounds for use in diagnostic and therapeutic medicine requires a diverse skill set. This article highlights a selection of our ongoing projects that aim to provide new synthetic methods and radiochemical tools for building molecular imaging agents with various radionuclides.
Keywords
- antibodies
- bioconjugation
- coordination chemistry
- copper
- density functional theory
- gallium
- photochemistry
- graphene
- positron emission tomography
- protein degradation
- radiochemistry
- zirconium
