PLoS ONE (Jan 2022)

Quantitative assessment of depolarization by the retinal pigment epithelium in healthy and glaucoma subjects measured over a large field of view.

  • Alice R Motschi,
  • Florian Schwarzhans,
  • Sylvia Desissaire,
  • Stefan Steiner,
  • Hrvoje Bogunović,
  • Philipp K Roberts,
  • Clemens Vass,
  • Christoph K Hitzenberger,
  • Michael Pircher

DOI
https://doi.org/10.1371/journal.pone.0278679
Journal volume & issue
Vol. 17, no. 12
p. e0278679

Abstract

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We present measurements of depolarization introduced by the retinal pigment epithelium (RPE) over a 45° field of view using polarization sensitive optical coherence tomography. A detailed spatial distribution analysis of depolarization caused by the RPE is presented in a total of 153 subjects including both healthy and diseased eyes. Age and sex related differences in the depolarizing character of the RPE are investigated.