mBio
(Feb 2021)
Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions
- Masayuki Nakajima,
- Masashi Matsuyama,
- Mio Kawaguchi,
- Takumi Kiwamoto,
- Yosuke Matsuno,
- Yuko Morishima,
- Kazufumi Yoshida,
- Mingma Sherpa,
- Kai Yazaki,
- Hajime Osawa,
- Masafumi Muratani,
- Yukio Ishii,
- Nobuyuki Hizawa
Affiliations
- Masayuki Nakajima
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Masashi Matsuyama
- ORCiD
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Mio Kawaguchi
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Takumi Kiwamoto
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Yosuke Matsuno
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Yuko Morishima
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Kazufumi Yoshida
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Mingma Sherpa
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Kai Yazaki
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Hajime Osawa
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Masafumi Muratani
- Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan
- Yukio Ishii
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- Nobuyuki Hizawa
- Department of Respiratory Medicine, Division of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
- DOI
-
https://doi.org/10.1128/mBio.01947-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
Read online
Nontuberculous mycobacteria (NTM) are an important cause of morbidity and mortality in pulmonary infections. Among them, Mycobacterium avium
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