Фундаментальная и клиническая медицина (Sep 2016)
TERMS OF RETINOBLASTOMA DIAGNOSIS IN PATIENTS WITH DISTINCT SIGNS AND SYMPTOMS
Abstract
Aim: To study the features of retinoblastoma (Rb) diagnosis in patients with different signs and symptoms. Materials and Methods: We investigated case histories of 58 patients (77 eyes) with Rb (1984-2013). Results: Average delay in diagnosis of Rb was 3.4 (95% CI 2.13-4.70) months. Average age of patients at diagnosis was 1.4-fold higher than at onset of symptoms (p = 0.001).The majority of patients (64%) had T3 and T4 stages according to the TNM classification. Conclusions: The results confirm the need in the measures aimed at early diagnosis of Rb within the first days of life. We suggest clinical and diagnostic algorithm for early detection of Rb.
