Relationship Between Intestinal Microflora and Uterine Myoma

Abstract

Objective To analyze the level of intestinal flora in uterine myoma patients and normal women, and to explore the correlation between intestinal flora and uterine myoma. Methods We selected 70 female patients with uterine myoma treated in our hospital from June 2015 to July 2017 as the study subjects, and 70 healthy women as control group. The feces of two groups were collected to extract their DNA and measure the number of intestinal flora. The levels of intestinal microflora were compared between the two groups, and the correlation between intestinal flora and the occurrence of uterine myoma was analyzed. Results Compared with the control group, total bacterial count and lactobacillus levels were significantly higher, and the levels of bifidobacterium, bacteroidetes, fusobacterium and proteus species were significantly lower in uterine myoma group (all P < 0.05). Total number of bacteria, bifidobacterium and lactobacillus were positively correlated, while bacteroides, clostridium and proteus were negatively correlated with the occurrence of uterine myoma (all P < 0.05). Conclusion There is correlation of the number and species of intestinal flora with the occurrence of uterine myoma.

Keywords

• intestinal flora
• uterine myoma
• correlation