Successful clozapine re-challenge in a patient with three previous episodes of clozapine-associated blood dyscrasia
Jessica Foster,
John Lally,
Victoria Bell,
Sukhi Shergill
Affiliations
Jessica Foster
National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK
John Lally
South London and Maudsley NHS Foundation Trust, London, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (loPPN), King's College London, London, UK; National Psychosis Unit, Department of Psychiatry, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin, Ireland
Victoria Bell
National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK
Sukhi Shergill
National Psychosis Unit, South London and Maudsley NHS Foundation Trust, London, UK; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK
A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service. We describe the history of clozapine trials and associated episodes of agranulocytosis and neutropenia, followed by the successfully tolerated third clozapine re-challenge within our service.
