Gold-catalyzed intermolecular hydroamination of allenes with sulfonamides

Abstract

A co-catalyst of (PPh3)AuCl/AgOTf for the intermolecular hydroamination of allenes with sulfonamides is shown. The reaction proceeded smoothly under mild conditions for differently substituted allenes giving N-allylic sulfonamides in good yields with high regioselectivity and E-selectivity.

Keywords

• allene
• gold catalysis
• hydroamination
• N-sulfonyl
• selectivity
• sulfonamide