Ixekizumab

Abstract

Ixekizumab is a human immunoglobulin G4 monoclonal antibody targeting interleukin-17A. Clinical trials have reported that 82-84% of the patients using ixekizumab achieved a PASI90 response at week 12 and 85% at week 60. It has been found effective in chronic plaque psoriasis as well as genital, hairy skin, nail, and generalized pustular psoriasis in adults. It has been approved by the FDA for use in moderate psoriasis in patients aged between 6 and 18 years.

Keywords

• anti-il-17
• ixekizumab
• psoriasis