Applied Sciences (Nov 2023)

Relationship between Carotid Artery Calcification and Periodontitis in the Saudi Population: A Retrospective Study

  • Wael I. Ibraheem,
  • Ashok Kumar Bhati,
  • Manar Ali Alhomood,
  • Omaima Ahmed Allayl,
  • Alzhouor Ali Qsadi,
  • Tahani Ibrahim Mnaji Mohammed,
  • Yahya Sulaiman Aljabri

DOI
https://doi.org/10.3390/app132212370
Journal volume & issue
Vol. 13, no. 22
p. 12370

Abstract

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Background: Atherosclerosis is the primary cause of cardiovascular death, wherein plaque accumulates in the carotid artery, resulting in the formation of carotid artery calcification (CAC). Chronic infections emulate atherosclerosis development. Periodontitis is a chronic disease commenced by biofilm aggregation on the surface of teeth, which then progresses via deregulated local and inflammatory immune responses. Aim: The aim of this study was to determine the prevalence of calcification in periodontitis patients and to determine if there is a relationship between carotid calcification and periodontitis with risk factors such as age, gender, hypertension, diabetes, smoking. Methods: The data and panoramic radiographs (PR) of 3000 patients from January 2017 to February 2022 were examined. On the basis of the inclusion and exclusion criteria, 500 patients were selected for determining carotid calcification. Non-periodontitis patients, patients U-tests were used to compare the distribution of the variables across the groups, and p-values < 0.05 were interpreted as statistically significant. Result: Twenty-five (5%) patients showed carotid calcification. Carotid calcification was seen more in females than in males, which was statistically significant. Gender, percentage of alveolar bone loss and periodontal risk were found to be statistically significantly related to carotid artery calcification. Factors such as age, diabetes and hypertension were found to be statistically nonsignificant. Conclusions: More periodontal destruction was present in the CAC patients. Within the limitations of this study, it can be concluded that CAC is associated with periodontitis. Early recognition of carotid calcification is important, and patients in whom carotid artery calcification is observed via their PR should be referred to medical practitioners for further investigation and treatment care.

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