Urine creatinine in treatment-naïve HIV subjects in eastern Nigeria

Abstract

INTRODUCTION: human immunodeficiency virus (HIV) infection is a global healthcare problem. Some diseases and physiological states may be altered in HIV-infected individuals. Our objective was to evaluate urine creatinine and factors that influence urine creatinine in treatment-naïve HIV subjects in Nigeria. METHODS: this was a cross-sectional study involving treatment-naïve HIV subjects in a tertiary hospital in Nigeria. Creatinine in spot and 24-hour urine samples and other relevant investigations were performed. Low urine creatinine or dilute urine was defined as 24-hour urine creatinine (24HUCr) =300mg, normal urine creatinine as 24HUCr 300-3000mg and high urine creatinine or concentrated urine as 24HUCr=3000mg.Theassociation of low urine creatinine and high urine creatinine with potentialrisk factors was determined.

Keywords

• hiv
• urine creatinine
• associated factors
• nigeria