Psoriasis: Targets and Therapy (Aug 2019)
A narrative review of psoriasis and multiple sclerosis: links and risks
Abstract
Annika S Silfvast-Kaiser,1 Katie B Homan,2 Bobbak Mansouri3–51Department of Dermatology, Baylor Scott and White, Dallas, TX, USA; 2Department of Dermatology, Baylor Scott and White Medical Center, Temple, TX, USA; 3Austin Institute for Clinical Research, Pflugerville, TX, USA; 4Sanova Dermatology – Pflugerville, Pflugerville, TX, USA; 5U.S. Dermatology Partners - Tyler, TX, USACorrespondence: Bobbak MansouriUS Dermatology Partners - Tyler, TX 1367 Dominion Plaza, Pflugerville, TX 75703, USAEmail [email protected]: The association of psoriasis (PsO) with other autoimmune and autoinflammatory diseases has long been a topic of interest. Although previous studies have attempted to clarify the specific relationship between PsO and multiple sclerosis (MS), it remains obscure, with limited and conflicting evidence regarding a link between the two entities. Herein, we review the etiology, pathogenesis, and treatment of each disease and present the available literature to-date regarding a possible relationship between PsO and MS. We conclude that further study is necessary to discern whether there may be a significant relationship between PsO and MS. In the meantime, clinicians may find it appropriate to screen for MS in patients with PsO, allowing for timely referral to a neurologist should it be necessary.Keywords: psoriasis, multiple sclerosis, incidence, prevalence, links, risk factors
