Cuffless Blood Pressure Estimation with Confidence Intervals using Hybrid Feature Selection and Decision Based on Gaussian Process

Abstract

Cuffless blood pressure (BP) monitoring is crucial for patients with cardiovascular disease and hypertension. However, conventional BP monitors provide only single-point estimates without confidence intervals. Therefore, the statistical variability in the estimates is indistinguishable from the intrinsic variability caused by physiological processes. This study introduced a novel method for improving the reliability of BP and confidence intervals (CIs) estimations using a hybrid feature selection and decision method based on a Gaussian process. F-test and robust neighbor component analysis were applied as feature selection methods for obtaining a set of highly weighted features to estimate accurate BP and CIs. Akaike’s information criterion algorithm was used to select the best feature subset. The performance of the proposed algorithm was confirmed through experiments. Comparisons with conventional algorithms indicated that the proposed algorithm provided the most accurate BP and CIs estimates. To the best of the authors’ knowledge, the proposed method is currently the only one that provides highly reliable BP and CIs estimates. Therefore, the proposed algorithm may be robust for concurrently estimating BP and CIs.

Keywords

• cuffless blood pressure estimation
• confidence interval
• Gaussian processing
• hybrid feature selection and decision
• F-test
• Akaike’s information criterion