The Multifunctional Role of Herbal Products in the Management of Diabetes and Obesity: A Comprehensive Review
Md. Mominur Rahman,
Md. Rezaul Islam,
Sheikh Shohag,
Md. Emon Hossain,
Md. Saidur Rahaman,
Fahadul Islam,
Muniruddin Ahmed,
Saikat Mitra,
Mayeen Uddin Khandaker,
Abubakr M. Idris,
Kumarappan Chidambaram,
Talha Bin Emran,
Simona Cavalu
Affiliations
Md. Mominur Rahman
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Md. Rezaul Islam
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Sheikh Shohag
Department of Biochemistry and Molecular Biology, Faculty of Life Science, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh
Md. Emon Hossain
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Md. Saidur Rahaman
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Fahadul Islam
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Muniruddin Ahmed
Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh
Saikat Mitra
Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh
Mayeen Uddin Khandaker
Centre for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway, Petaling Jaya 47500, Malaysia
Abubakr M. Idris
Department of Chemistry, College of Science, King Khalid University, Abha 62529, Saudi Arabia
Kumarappan Chidambaram
Department of Pharmacology and Toxicology, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia
Talha Bin Emran
Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh
Simona Cavalu
Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania
Obesity and diabetes are the most demanding health problems today, and their prevalence, as well as comorbidities, is on the rise all over the world. As time goes on, both are becoming big issues that have a big impact on people’s lives. Diabetes is a metabolic and endocrine illness set apart by hyperglycemia and glucose narrow-mindedness because of insulin opposition. Heftiness is a typical, complex, and developing overall wellbeing worry that has for quite some time been connected to significant medical issues in individuals, all things considered. Because of the wide variety and low adverse effects, herbal products are an important hotspot for drug development. Synthetic compounds are not structurally diverse and lack drug-likeness properties. Thus, it is basic to keep on exploring herbal products as possible wellsprings of novel drugs. We conducted this review of the literature by searching Scopus, Science Direct, Elsevier, PubMed, and Web of Science databases. From 1990 until October 2021, research reports, review articles, and original research articles in English are presented. It provides top to bottom data and an examination of plant-inferred compounds that might be utilized against heftiness or potentially hostile to diabetes treatments. Our expanded comprehension of the systems of activity of phytogenic compounds, as an extra examination, could prompt the advancement of remedial methodologies for metabolic diseases. In clinical trials, a huge number of these food kinds or restorative plants, as well as their bioactive compounds, have been shown to be beneficial in the treatment of obesity.
