A multidisciplinary view of mastectomy and breast reconstruction: Understanding the challenges
Orit Kaidar-Person,
Birgitte V. Offersen,
Liesbeth J. Boersma,
Dirk de Ruysscher,
Trine Tramm,
Thorsten Kühn,
Oreste Gentilini,
Zoltán Mátrai,
Philip Poortmans
Affiliations
Orit Kaidar-Person
Breast Cancer Radiation Therapy Unit, At Sheba Medical Center, Ramat Gan, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; GROW-School for Oncology and Developmental Biology (Maastro), Maastricht University, Maastricht, the Netherlands; Corresponding author. Breast radiation therapy Unit, Sheba Medical Center, Sheba Tel Ha’shomer, Ramat Gan, Israel.
Birgitte V. Offersen
Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark
Liesbeth J. Boersma
GROW-School for Oncology and Developmental Biology (Maastro), Maastricht University, Maastricht, the Netherlands; Department of Radiation Oncology (Maastro), Maastricht University Medical Centre, Maastricht, the Netherlands
Dirk de Ruysscher
GROW-School for Oncology and Developmental Biology (Maastro), Maastricht University, Maastricht, the Netherlands; Department of Radiation Oncology (Maastro), Maastricht University Medical Centre, Maastricht, the Netherlands
Trine Tramm
Department of Pathology, Aarhus University Hospital, Denmark
Thorsten Kühn
Department of Gynaecology and Obstetrics, Interdisciplinary Breast Center, Klinikum Esslingen, Germany
Oreste Gentilini
Breast Surgery Unit, San Raffaele University Hospital, Milan, Italy
Zoltán Mátrai
Department of Breast and Sarcoma Surgery, National Institute of Oncology, Budapest, 1122, Budapest, Ráth György U 7, Hungary
Philip Poortmans
Iridium Kankernetwerk, 2610, Wilrijk-Antwerp, Belgium; University of Antwerp, Faculty of Medicine and Health Sciences, 2610, Wilrijk-Antwerp, Belgium
The current review paper was written in collaboration with breast cancer surgeons from the European Breast Cancer Research Association of Surgical Trialists (EUBREAST), a breast pathologist from the Danish Breast Cancer Group (DBCG), and representatives from the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer course. Herein we summarize the different mastectomies and reconstruction procedures and define high-risk anatomical areas for breast cancer recurrences, to further specify the challenges in the surgical procedure, histopathological evaluation, and target volumes in case of postmastectomy irradiation, as recommended by the ESTRO guidelines according to the surgical procedure. The paper has original figures and illustrations for all disciplines for in-depth understanding of the differences between the procedures.
