Revista do Instituto de Medicina Tropical de São Paulo (Mar 1999)

Paracoccidioides brasiliensis: A MYCOLOGIC AND IMMUNOCHEMICAL STUDY OF TWO STRAINS

  • Carlos da Silva LACAZ,
  • Mônica Scarpelli Martinelli VIDAL,
  • Elisabeth Maria HEINS-VACCARI,
  • Natalina Takahashi de MELO,
  • Gilda Maria Barbaro DEL NEGRO,
  • Giovana Letícia Hernandez ARRIAGADA,
  • Roseli dos Santos FREITAS

Journal volume & issue
Vol. 41, no. 2
pp. 79 – 86

Abstract

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The authors conducted a mycologic, immunochemical and molecular biology study on two strains of Paracoccidioides brasiliensis, one of them, called IBIÁ, isolated from soil in the municipality of IBIÁ (Minas Gerais) by Silva-Vergara et al. (l996,1998)20,21, and the other, BAT, cultivated from a human case of paracoccidioidomycosis in Ribeirão Preto (São Paulo/Brazil) by Freitas da Silva (l996)6. Both strains showed cotton-like (M) and yeast-like (Y) forms and were pathogenic for testicularly inoculated guinea pigs, producing granulomatous and/or suppurative orchitis. Immunochemically was demonstrated the presence of gp43 by double immunodiffusion, immunoelectrophoresis and immunoblotting.

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