American Journal of Ophthalmology Case Reports (Sep 2022)

Iris pigment epithelial (IPE) cysts secondary to Hodgkin's lymphoma: A case report

  • Elien Willekens,
  • Veva De Groot,
  • Karolien Beel,
  • Kim De Muynck,
  • Pieter-Paul Schauwvlieghe

Journal volume & issue
Vol. 27
p. 101597

Abstract

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Purpose: To describe a unique case of a white male who presented with reduced visual acuity, growing bilateral iris pigment epithelial (IPE) cysts and granulomatous panuveitis, probably related to Hodgkin's lymphoma. Observations: The granulomatous panuveitis was reactive to corticosteroids, but the IPE cysts were not. After extensive work-up, the patient was diagnosed with Hodgkin's lymphoma (HL) mixed cellularity type with cervical and mediastinal lymph node involvement. After starting chemotherapy, the IPE cysts shrank. Conclusions and importance: To our knowledge, IPE cysts have not been described in HL before. Therefore, this case can contribute to our knowledge of the relation between IPE cysts and hematological malignancy.

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