High content genome-wide siRNA screen to investigate the coordination of cell size and RNA production

Abstract

Measurement(s) nascent RNA • Image • S phase • nucleolus organization • Cellular Morphology • Cell Cycle Phase Technology Type(s) metabolic labelling: 5-ethynyl uridine • spinning-disk confocal microscope • supervised machine learning • Image Processing Factor Type(s) gene expression Sample Characteristic - Organism HeLa cell Sample Characteristic - Environment cell culture Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.14332916