Emerging Infectious Diseases (Jul 2022)

SARS-CoV-2 Delta–Omicron Recombinant Viruses, United States

  • Kristine A. Lacek,
  • Benjamin L. Rambo-Martin,
  • Dhwani Batra,
  • Xiao-yu Zheng,
  • Norman Hassell,
  • Hitoshi Sakaguchi,
  • Thomas Peacock,
  • Natalie Groves,
  • Matthew Keller,
  • Malania M. Wilson,
  • Mili Sheth,
  • Morgan L. Davis,
  • Mark Borroughs,
  • Jonathan Gerhart,
  • Samuel S. Shepard,
  • Peter W. Cook,
  • Justin Lee,
  • David E. Wentworth,
  • John R. Barnes,
  • Rebecca Kondor,
  • Clinton R. Paden

DOI
https://doi.org/10.3201/eid2807.220526
Journal volume & issue
Vol. 28, no. 7
pp. 1442 – 1445

Abstract

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To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta–Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and validated 9 genetically related SARS-CoV-2 viruses with a hybrid Delta–Omicron spike protein.

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