Journal of Hepatocellular Carcinoma (Oct 2023)

Efficacy and Safety of Microwave Ablation Assisted by Ultrasound Fusion Imaging for Primary and Secondary Liver Cancers with a Diameter of 3–7 Cm

  • Yang J,
  • Liang S,
  • Liu H,
  • Hu C,
  • Guan S,
  • Kang H,
  • Xu E,
  • Yan R

Journal volume & issue
Vol. Volume 10
pp. 1839 – 1848

Abstract

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Jing Yang,1,* Shuang Liang,1,* Huahui Liu,1 Cai Hu,1 Sainan Guan,1 Haiyu Kang,1 Erjiao Xu,1 Ronghua Yan1,2 1Department of Medical Ultrasonics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong Province, People’s Republic of China; 2Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ronghua Yan; Erjiao Xu, Department of Medical Ultrasonics, The Eighth Affiliated Hospital of Sun Yat-sen University, No. 3025 Shennan Middle Road, Futian Street, Futian District, Shenzhen City, Guangdong Province, People’s Republic of China, Tel +86 755 83982222, Fax +86 755 83980805, Email [email protected]; [email protected]: To investigate the efficacy and safety of microwave ablation (MWA) assisted by ultrasound fusion imaging (FI) for primary and secondary liver cancers with a diameter of 3– 7 cm.Patients and Methods: A retrospective analysis was conducted on patients with primary and secondary liver cancers (3– 7 cm) who underwent MWA with ultrasound FI assistance in our hospital from April 2020 to May 2022. Technical success, technique efficacy, local tumor progression (LTP), major complication, intrahepatic distant recurrence (IDR), and overall survival (OS) were assessed during the follow-up period. In addition, the ablation results of tumors between the medium-sized group (3.1– 5.0 cm) and large-sized group (5.1– 7.0 cm) were compared.Results: 31 patients with 35 primary and secondary liver cancers were treated with MWA assisted by ultrasound FI. Complete ablation was achieved in 34 lesions with a technical success rate of 97.1%. Major complications occurred in 6.5% of patients (2/31), while no ablation-related deaths were reported. The median follow-up time of this study was 24 months (range:10 to 35 months). The technique efficacy rate was 97.1% (34/35), with LTP occurring in three lesions at a rate of 8.8% (3/34). The incidence of IDR was 38.7% (12/31) and the 2-year cumulative OS rate reached 96.7%. Moreover, there were no statistical differences in technique efficacy rate (p=0.286), LTP rate (p=0.328), major complication rate (p=0.503), IDR (p=0.857), and OS (p=0.118) between medium-sized group and large-sized group.Conclusion: Ultrasound FI-assisted MWA has the potential to be an effective and safe therapeutic strategy for primary and secondary liver cancers ranging from 3– 7 cm in size.Keywords: fusion imaging, microwave ablation, liver cancers, ultrasound

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