Kemija u Industriji (Nov 2014)

A Method for Optimizing Technical Parameters of the Vacuum Freeze-Drying Process

  • Qian, X.-M.,
  • Huang, W.-R.,
  • Lou, P.-H.

DOI
https://doi.org/10.15255/KUI.2013.011
Journal volume & issue
Vol. 63, no. 7-8
pp. 265 – 268

Abstract

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Vacuum freeze-drying is a technique that makes a material dehydrate at low temperature and low pressure, and it has many merits. A control system is designed and developed based on a certain area freeze-drying machine. A test by the control system is done to optimize the freeze-drying technical parameters. According to the test results, by the method of quadratic orthogonal experiment, the key parameters, including duration, temperature and vacuum of freeze-drying, are analysed and optimized. The test proves the optimized parameters valid for certain vacuum freeze-drying machines and certain bacterins. Furthermore, the optimized parameters show that the vacuum freeze-drying method is useful for any area vacuum freeze-drying machine and any bacterin.

Keywords