138 Shared frameshift neoantigens are expressed throughout mismatch repair deficient cancer development and are recognized by tissue infiltrating T cells that are dysregulated in advanced lesions

• Matthew Brown,
• Nina Bhardwaj,
• Cansu Cimen Bozkus,
• Aimee L Lucas,
• Alexandros D Polydorides,
• Leandra Velazquez,
• Mesude Bicak,
• Juhana Habib,
• Sharonne Holtzman,
• Mona Saleh,
• Robert Samstein

Affiliations

Matthew Brown

1Icahn School of Medicine at Mount Sinai, New York, NY, USA

Nina Bhardwaj

3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Cansu Cimen Bozkus

3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Aimee L Lucas

1Icahn School of Medicine at Mount Sinai, New York, NY, USA

Alexandros D Polydorides

5Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Leandra Velazquez

3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Mesude Bicak

3Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Juhana Habib

2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Sharonne Holtzman

4Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Mona Saleh

4Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Robert Samstein

7Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA