Pediatric Health, Medicine and Therapeutics (Nov 2023)

Prevalence of Bradycardia After Induction of General Anesthesia and Associated Factors Among Surgical Pediatric Patients. A Prospective Observational Study

  • Ilala TT,
  • Teku Ayano G,
  • Seife MA,
  • Yinges Kebede M,
  • Geleta BA,
  • Tamrat Yilma K

Journal volume & issue
Vol. Volume 14
pp. 419 – 434

Abstract

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Tajera Tageza Ilala, Gudeta Teku Ayano, Minda Abebe Seife, Mengistu Yinges Kebede, Belete Alemu Geleta, Kidanemariam Tamrat Yilma Department of Anesthesia, College of Medicine and Health Science, Hawassa University, Hawassa, EthiopiaCorrespondence: Tajera Tageza Ilala, Department of Anesthesia, College of medicine and Health Science, Hawassa University, Hawassa, Ethiopia, Email [email protected]: Heart rate is the main determinant factor of the child’s cardiac output in the first year of life. Thus, bradycardia decreases cardiac output leading to fatal cardiac arrhythmias, cardiac arrest, and even death. The objective of this study is to determine the prevalence of bradycardia and its associated factors after induction of general anesthesia among pediatric patients operated at Hawassa University Comprehensive Specialized Hospital (HUCSH).Methods: Prospective observational study was employed at HUCSH by using a systematic random sampling technique. Pediatric surgical patients less than 6 years old were included in the study. Data were entered into Epi data statistical software (version 4.6.0.) and exported to SPSS (version 25.0). Categorical data were analyzed using chi-square statistics, and continuous data were analyzed using Student’s t-test. Bivariable logistic regression was used to select candidate variables for multivariable logistic regression.Results: The prevalence of bradycardia among 205 pediatric patients included in this study was 19.5%. Preoperative risk of hypoxia, opioids premedication, inhalational induction (halothane), difficult intubation, intraoperative complications, and significant surgical blood loss were independently associated with bradycardia.Conclusion: The prevalence of bradycardia after induction of general anesthesia was 19.5%. Preoperative risk of hypoxia, opioids premedication, inhalational induction (particularly with halothane), difficult intubation, intraoperative complications such as hypoxia, and significant blood loss were significantly associated with bradycardia.Keywords: anesthesia, bradycardia, general anesthesia, induction of anesthesia, pediatrics bradycardia, pediatrics surgery

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