The use of immunofluorescence antigen mapping in the diagnosis of junctional epidermolysis bullosa in a 15-year-old female

Abstract

Epidermolysis bullosa (EB) comprises a group of genetically determined skin fragility disorders, characterized by blistering of the skin and mucosae following mechanical trauma, which includes four major forms (EB simplex, junctional EB [JEB], dystrophic EB, and Kindler syndrome) with various distinctive clinical phenotypes. We report a rare case of a 15-year-old female diagnosed as JEB (generalized intermediate), with the help of immunofluorescence antigen mapping.

Keywords

• immunofluorescence antigen mapping
• junctional epidermolysis bullosa
• laminin 332